abstract：:A comparison has been made of the membrane glycoproteins and glycopeptides from two enveloped viruses, Sindbis virus and vesicular stomatitis virus (VSV). Glycopeptides isolated from Sindbis virus and VSV grown in the same host appear to differ principally in the number of sialic acid residues per glycopeptide; when s...

journal_title：Journal of virology

authors： Burge BW,Huang AS

更新日期：1970-08-01 00:00:00

abstract：:Polyoma virus particles were purified by equilibrium centrifugation in CsCl. Particles from three regions of the density gradient were examined for infectivity, for their ability to induce expanded pools of deoxyribonucleic acid (DNA) precursors, and for their ability to stimulate the synthesis of DNA. The most infect...

journal_title：Journal of virology

authors： Skoog L,Nordenskjöld BA,Lindberg U

更新日期：1970-07-01 00:00:00

abstract：:The structure of Bacillus subtilis bacteriophage phi25 and phi25 deoxyribonucleic acid (DNA) were studied by electron microscopy. The head of phi25 is a regular polyhedron measuring 75 nm in diameter. The uncontracted tail of phi25 is 130 nm in length and includes a large, complex tail plate. Phage phi25 DNA is double...

journal_title：Journal of virology

authors： Liljemark WF,Anderson DL

更新日期：1970-07-01 00:00:00

abstract：:A ribonucleic acid (RNA)-dependent RNA polymerase was induced in chick embryo fibroblast cells after infection with Sendai virus (parainfluenza 1 virus). The enzyme was associated with the microsomal fraction of infected cells and reached maximum detectable activity at 18 hr after virus infection. The activity of the ...

journal_title：Journal of virology

authors： Mahy BW,Hutchinson JE,Barry RD

更新日期：1970-06-01 00:00:00

abstract：:Feline herpesvirus produces characteristic morphological alterations in feline kidney cells. Nucleocapsid particles are formed in infected nuclei and are enveloped as they pass through the modified inner nuclear membrane. Aggregates of dense granular material and filamentous structures also regularly appear in infecte...

journal_title：Journal of virology

authors： Abraham A,Tegtmeyer P

更新日期：1970-05-01 00:00:00

abstract：:Phenol-extracted, infectious deoxyribonucleic acid (DNA) species from phi105 phage particles, from phi105 lysogenic bacteria, and from induced phi105 lysogenic bacteria were sedimented in sucrose gradients. Infectious DNA from phi105 particles sedimented like the bulk of mature phage DNA in neutral sucrose. Infectivit...

journal_title：Journal of virology

authors： Rutberg L,Rutberg B

更新日期：1970-05-01 00:00:00

abstract：:The two canine adenoviruses, infectious canine hepatitis (ICH) virus and infectious canine laryngotracheitis (ICL) virus (also designated as Toronto A26/61 virus), were studied with respect to their morphology and the biological properties of their soluble components. The two viruses were found to be composed of solub...

journal_title：Journal of virology

authors： Marusyk RG,Norrby E,Lundqvist U

更新日期：1970-04-01 00:00:00

abstract：:Skin fibroblast cultures were established from eight individuals. These cell cultures, together with WI-38 cells, were examined for susceptibility to transformation by SV40 virus. Four transformation-susceptible cell lines (TS), established from patients with Down's syndrome, were found to be three to four times more ...

journal_title：Journal of virology

authors： Potter CW,Potter AM,Oxford JS

更新日期：1970-03-01 00:00:00

abstract：:The time course and extent of mengovirus production were the same in metaphase-arrested and interphase L-cells, yet the expression of cytopathology was delayed several hours in metaphase cells. ...

journal_title：Journal of virology

authors： Lake RS,Winkler DC,Ludwig EH

更新日期：1970-02-01 00:00:00

abstract：:The presence of cycloheximide, an inhibitor of protein synthesis, during the period 30 to 60 min after vaccinia infection produced an irreversible block in virus replication. In contrast (i) cycloheximide given at earlier or later times, even for prolonged periods, did not prevent continuation of the infectious cycle ...

journal_title：Journal of virology

authors： Mss B,Filler R

更新日期：1970-02-01 00:00:00

abstract：:Mouse mammary tumor virus (MTV) was isolated from the milk of RIII mice by density-gradient centrifugation in Ficoll. The homogeneity of the preparation was demonstrated in electron micrographs. The nucleic acid was extracted with phenol in the presence of Pronase. Its viral origin was attested by failure of ribo-nucl...

journal_title：Journal of virology

authors： Sarkar NH,Moore DH

更新日期：1970-02-01 00:00:00

abstract：:Duck embryo fibroblast (DEF) and chicken embryo fibroblast (CEF) cultures infected with Marek's disease virus were studied by combined fluorescent antibody and electron microscopy techniques. In both DEF and CEF cultures, cells containing immunofluorescent (IF) antigen also contained herpesvirus particles; conversely,...

journal_title：Journal of virology

authors： Nazerian K,Purchase HG

更新日期：1970-01-01 00:00:00

abstract：:Forty isolates of herpes simplex virus were compared by means of cross-neutralization curves. The 11 oral isolates were serotype 1, and all 29 genital/anal isolates were serotype 2. The cytopathic effects of the two serotypes were consistently different. Passage of strains of type 1 and type 2 in mice and in rabbits y...

journal_title：Journal of virology

authors： Plummer G,Waner JL,Phuangsab A,Goodheart CR

更新日期：1970-01-01 00:00:00

abstract：:Infection by rat virus has been studied in cultures of rat embryo cells to evaluate the Margolis-Kilham hypothesis that the virus preferentially infects tissues with actively dividing cells. An enhancement of infection was seen in cultures infected 10 hr after fresh medium was added as compared to infection of station...

journal_title：Journal of virology

authors： Tennant RW,Layman KR,Hand RE

更新日期：1969-12-01 00:00:00

abstract：:The conversion of simian virus 40 (SV40) component II deoxyribonucleic acid to component I has been used to assay polynucleotide ligase in extracts of tissue culture cells. All cell types examined, including chicken, hamster, mouse, monkey, and human cells, contained adenosine triphosphate-dependent ligase. After infe...

journal_title：Journal of virology

authors： Sambrook J,Shatkin AJ

更新日期：1969-11-01 00:00:00

abstract：:A continuous cell line of highly contact-inhibited cells (NIH/3T3) has been developed from NIH Swiss mouse embryo cultures. Its growth properties are similar to those of 3T3 and BALB/3T3. Although 3T3 is relatively insensitive to focus formation by murine sarcoma viruses, cloned lines of both NIH/3T3 and BALB/3T3 have...

journal_title：Journal of virology

authors： Jainchill JL,Aaronson SA,Todaro GJ

更新日期：1969-11-01 00:00:00

abstract：:Cultural changes that follow infection of rabbit kidney cells with fibroma virus were studied. Characteristic alterations of cell morphology and development of multilayered piles and cords of cells were found to occur in infected cultures in which cell division was blocked by gamma radiation or by cell crowding and se...

journal_title：Journal of virology

authors： Tompkins WA,Walker DL,Hinze HC

更新日期：1969-11-01 00:00:00

abstract：:The serological relationship of the ribonucleic acid (RNA)-containing coliphages MS-2, M-12, R-17, f(2), beta, fr, f(4), and Qbeta was determined. Antisera against MS-2, R-17, f(2), fr, and Qbeta neutralized the infectivity of all of these RNA phages to varying degrees. Although each phage was serologically distinct, ...

journal_title：Journal of virology

authors： Krueger RG

更新日期：1969-11-01 00:00:00

abstract：:Purified Kunjin virus was disrupted with sodium dodecyl sulfate, urea, and mercaptoethanol or acetic acid. Electrophoresis on 7.5% polyacrylamide gel separated four proteins of high (120,000), intermediate (65,000) and low (18,000 and 13,000) molecular weights. A "core" particle was obtained by degradation of the viri...

journal_title：Journal of virology

authors： Westaway EG,Reedman BM

更新日期：1969-11-01 00:00:00

abstract：:The ribonucleic acid (RNA) of murine leukemia virus (MLV) Rauscher strain was observed by the aid of electron microscopy with the use of the protein monolayer technique. RNA was observed directly after release from virus particles or after isolation by sedimentation in sucrose density gradients. Molecules were found i...

journal_title：Journal of virology

authors： Kakefuda T,Bader JP

更新日期：1969-10-01 00:00:00

abstract：:Polypeptide synthesis has been studied in cell-free systems prepared from vaccinia virus-infected and uninfected HeLa cells. Cytoplasmic extracts containing endogenous messenger ribonucleic acid were used. Amino acid incorporation into hot trichloroacetic acid-precipitable material was linear for 15 to 20 min at 37 C....

journal_title：Journal of virology

authors： Katz E,Moss B

更新日期：1969-10-01 00:00:00

abstract：:Striking morphologic similarities between Machupo, Tacaribe, and lymphocytic choriomeningitis viruses were found by thin-section electron microscopy. It is proposed that these viruses be brought together into a single taxonomic group. ...

journal_title：Journal of virology

authors： Murphy FA,Webb PA,Johnson KM,Whitfield SG

更新日期：1969-10-01 00:00:00

abstract：:A rat nephroma cell line was found to be a carrier culture of the Kilham rat virus. Infectious virus was demonstrable only by passage of culture materials into other host systems. ...

journal_title：Journal of virology

authors： Wozniak J,Hetrick F

更新日期：1969-09-01 00:00:00

abstract：:The strain of Newcastle disease virus (NDV(pi)) present in persistently infected L cells differed markedly from the Herts strain (NDV(0)) used to initiate the infection. NDV(pi) produced small plaques (less than 1 mm) in chick embryo cell cultures, whereas the wild type (NDV(0)) produced large plaques (2 to 3 mm). The...

journal_title：Journal of virology

authors： Thacore H,Youngner JS

更新日期：1969-09-01 00:00:00

abstract：:The interrelationship of viral ribonucleic acid (RNA) and protein synthesis in cells infected by Sindbis virus was investigated. When cultures were treated with puromycin early in the course of infection, the synthesis of interjacent RNA (26S) was preferentially inhibited. A similar result was obtained by shifting cel...

journal_title：Journal of virology

authors： Scheele CM,Pfefferkorn ER

更新日期：1969-08-01 00:00:00

abstract：:Chick embryo cells became more sensitive to the action of interferon the longer they remained in culture. This phenomenon was found even before confluency had been reached. The relative insensitivity of newly seeded cells was not due to a loss of receptors. Cells synthesizing deoxyribonucleic acid (DNA) at a high rate...

journal_title：Journal of virology

authors： Rossman TG,Vilcek J

更新日期：1969-07-01 00:00:00

abstract：:"L-cell virion," obtained from chronically infected 929 L-cell lines, was purified on 70% sucrose pads and its ribonucleic acid (RNA) was extracted and analyzed on sucrose gradients. Two RNA components were isolated from the virion, a rapidly sedimenting species (82S) and a more slowly sedimenting species (6S). When t...

journal_title：Journal of virology

authors： Faras AJ,Erikson RL

更新日期：1969-07-01 00:00:00

abstract：:Intranuclear and intracytoplasmic inclusions in monkey kidney cells infected with African horsesickness virus were studied with the aid of electron microscopy. ...

journal_title：Journal of virology

authors： Breese SS Jr,Ozawa Y

更新日期：1969-07-01 00:00:00

abstract：:Grasshoppers, Melanoplus sanguinipes (F.), infected with the grasshopper inclusion body virus (GIBV) showed a general torpor, took longer to develop, and had abnormally high rates of mortality. Infection was found only in the fat body, and developing viruses and inclusion bodies were observed in the nuclei and cytopla...

journal_title：Journal of virology

authors： Henry JE,Nelson BP,Jutila JW

更新日期：1969-06-01 00:00:00

abstract：:Inhibitors of hemagglutination by type A2 influenza virus and a recently isolated strain of type B influenza virus were separated by sucrose density gradient centrifugation and agarose gel filtration from horse serum. Using selected reagents, it was demonstrated that the active substituent on the horse serum inhibitor...

journal_title：Journal of virology

authors： Levinson B,Pepper D,Belyavin G

更新日期：1969-05-01 00:00:00

abstract：:Circulating interferon production, induced by Newcastle disease virus, is about seven times higher in C(57) Black mice than i Balb/c/Gif mice. A Mendelian analysis was carried out and circulating interferon production was measured in reciprocal F(1) hybrids, in the F(2) generation, in progeny of backcrosses of F(1) hy...

journal_title：Journal of virology

authors： de Maeyer E,de Maeyer-Guignard J

更新日期：1969-05-01 00:00:00

abstract：:Induction of the resident prophage did not permit restricted phage T1 to replicate freely in P1-lysogenic hosts. A few induced cells did become infectible. ...

journal_title：Journal of virology

authors： Christensen JR,Werner ER

更新日期：1969-04-01 00:00:00

abstract：:Analyses, by construction of phage growth curves, indicated that the polysaccharide depolymerase was synthesized by Pseudomonas aeruginosa strains B and BI after infection with phage 2. The kinetics of biosynthesis of the depolymerase were found to parallel closely the rate of formation of phage-directed virions, and ...

journal_title：Journal of virology

authors： Bartell PF,Orr TE

更新日期：1969-03-01 00:00:00

abstract：:Yaba tumor poxvirus deoxyribonucleic acid (DNA) has a density of 1.6905 in CsCl and its T(m) value in 0.015 m citrate in saline is 82.3. The guanine plus cytosine content estimated from these properties was taken to be 32.5 +/- 0.5%, a value 2 to 3% less than for DNA from other poxviruses reported to date. ...

journal_title：Journal of virology

authors： Yohn DS,Gallagher JF

更新日期：1969-02-01 00:00:00

abstract：:Dactylosporangiophage A1 has a polygonal head (75 nm) with spherical capsomeres (3 nm) and a noncontractile tail (200 by 10 nm) with cross-striations which is terminated with at least three prongs which are used for attachment. It contains double-stranded deoxyribonucleic acid and produces very little lysis. Intracell...

journal_title：Journal of virology

authors： Higgins ML,Lechevalier MP

更新日期：1969-02-01 00:00:00

abstract：:Analysis of large and small plaque mutants of simian virus 40 using antisera prepared against each has revealed quantitative and possibly qualitative antigenic differences for each plaque type. A sensitive micro radioisotope precipitation test permitted evaluation of immunochemical similarities and differences of caps...

journal_title：Journal of virology

authors： Ozer HL,Takemoto KK,Kirschstein RL,Axelrod D

更新日期：1969-01-01 00:00:00

abstract：:Bacteriophage phi105 is a temperate bacteriophage for Bacillus subtilis 168. Temperature-sensitive and plaque mutants of phi105 were isolated. The results of two- and three-factor crosses with these mutants suggest the vegetative map of phi105 to be circular. The location of prophage phi105 between bacterial markers p...

journal_title：Journal of virology

authors： Rutberg L

更新日期：1969-01-01 00:00:00

abstract：:Purified Semliki Forest virus (SFV) contains three structural proteins while its core (nucleocapsid) contains two of these proteins. To identify all of the proteins synthesized under virus direction, cells were infected with SFV in the presence of actinomycin D and guanidine. Cell protein synthesis was markedly and ir...

journal_title：Journal of virology

authors： Friedman RM

更新日期：1968-10-01 00:00:00

abstract：:Small aggregates of viral antigen were encountered in the nuclear matrix. The capsids did not tag with antibodies specific for the virus or for the host cell. This observation remains unexplained. Nuclear and cytoplasmic membranes, as well as the envelope of the virus, reacted with both types of antibodies and appear,...

journal_title：Journal of virology

authors： Nii S,Morgan C,Rose HM,Hsu KC

更新日期：1968-10-01 00:00:00

abstract：:A marked virus-inhibiting potency is obtained in the serum after intraperitoneal injection of polyacrylic acid (PAA) and polymethacrylic acid (PMAA) in mice. Much higher antiviral levels were reached than for other related polymers including dextran sulfate, heparin, polyvinyl sulfate, pyran copolymer, polystyrene sul...

journal_title：Journal of virology

authors： De Somer P,De Clercq E,Billiau A,Schonne E,Claesen M

更新日期：1968-09-01 00:00:00